Table 1.

Overt anal tumors in E6/E7 mice treated with 0.12 μmol DMBA are more likely to be carcinoma

Histologic classification of disease
PhenotypenNormalHyperplasiaPapillomaAtypia (%)Cancer (%)a
Tumors140035 (36)6 (43)
No tumors176514 (24)1 (6)
  • aP < 0.05 comparing presence of cancer in E6/E7 mice with versus without tumors.