Overt anal tumors in E6/E7 mice treated with 0.12 μmol DMBA are more likely to be carcinoma
Histologic classification of disease | ||||||
---|---|---|---|---|---|---|
Phenotype | n | Normal | Hyperplasia | Papilloma | Atypia (%) | Cancer (%)a |
Tumors | 14 | 0 | 0 | 3 | 5 (36) | 6 (43) |
No tumors | 17 | 6 | 5 | 1 | 4 (24) | 1 (6) |
↵aP < 0.05 comparing presence of cancer in E6/E7 mice with versus without tumors.