Table 2

Changes in rectal biopsy genes induced by estradiol

Subject designationGenes changed after 4 wk of estradiol administrationGenes overlapping with estrogen-responsive genes in the ERGDBGenes overlapping with genes modulated in HCT116 cells by estradiol in vitro
nn%Pn%P
E1587467.80.002264.4NS
E31,3391279.5<0.00115811.8<0.001
E4846758.9<0.001698.2<0.001
E5744516.90.02648.6<0.001
E61,126665.9NS625.5NS
E71,11111610.4<0.0011079.6<0.001
E81,9371728.9<0.0011608.3<0.001
E9647446.8NS477.3NS
E106837110.4<0.0018111.9<0.001
E111,8261246.8<0.0011206.60.002

NOTE: Data are presented as number of genes that changed and number and percent of overlapping genes. P value determined by Fisher's exact test with Bonferroni correction.

Abbreviation: NS, not significant.