Table 4.

Change in histology measures

ObservationTreatedDifference* (treated − observed)
Difference95% CIP
All subjects
    n1936
    Maximum0.37 (2.34)0.03 (1.61)−0.18(−1.16 to 0.81)0.72
    Average0.14 (0.88)−0.17 (1.04)−0.25(−0.77 to 0.28)0.35
    Dysplasia index0.00 (0.29)−0.04 (0.26)−0.02(−0.16 to 0.12)0.75
Current smokers
    n915
    Maximum−0.56 (1.24)0.00 (1.81)0.69(−0.77 to 2.15)0.34
    Average0.01 (0.93)−0.32 (1.34)−0.19(−1.27 to 0.88)0.71
    Dysplasia index0.00 (0.35)−0.11 (0.32)−0.04(−0.33 to 0.24)0.76
Former smokers
    n1021
    Maximum1.20 (2.82)0.05 (1.50)−0.92(−2.31 to 0.47)0.18
    Average0.26 (0.87)−0.07 (0.78)−0.31(−0.84 to 0.23)0.25
    Dysplasia index0.01 (0.24)0.01 (0.20)0.00(−0.15 to 0.14)0.97
  • *Adjusted for baseline histology (either maximum, average, or index). All subject analysis is also adjusted for smoking status.