Table 5.

Baseline Ki67 levels

ObservationTreatedDifference (treated − observed)
Difference95% CIP
All subjects
    n2748
    Maximum38.42 (24.28)45.14 (26.65)6.89(−4.22 to 17.90)0.22
    Average18.51 (12.39)21.82 (13.60)3 41(−2.04 to 8.85)0.22
    Ki67 fraction0.40 (0.35)0.44 (0.31)0.04(−0.10 to 0.17)0.59
Current smokers
    n1221
    Maximum53.17 (21.33)57.29 (20.93)4.12(−11.43 to 19.08)0.59
    Average27.52 (10.53)28.62 (13.20)1.11(−7.99 to 10.20)0.81
    Ki67 fraction0.06 (0.30)0.59 (0.28)−0.06(−0.27 to 0.14)0.53
Former smokers
    n1527
    Maximum26.62 (20.04)35.70 (27.12)9.07(−7.11 to 25.26)0.26
    Average11.31 (8.53)16.54 (11.57)5.23(−1.68 to 12.13)0.13
    Ki67 fraction0.20 (0.25)0.32 (0.28)0.12(−0.06 to 0.30)0.19

NOTE: “All subject” analysis is adjusted for smoking status. Ki67 fraction is proportion of all samples within the individuals in which the Ki67 percentage exceeds 15%.