Table 1.

Distribution of descriptive characteristics for cases and controls

CharacteristicCases (n = 434)Controls (n = 547)P
Age (y)0.08
Mean ± SD59.68 ± 11.4160.99 ± 11.44
Gender0.83
    Female114 (26.27)147 (26.87)
    Male320 (73.73)400 (73.13)
Race0.94
    Caucasian389 (90.68)499 (91.22)
    African-American15 (3.5)19 (3.47)
    Other25 (5.83)29 (5.3)
    Missing50
Education<0.001
    Lower than high school76 (17.59)43 (7.88)
    High school or equivalence172 (39.81)203 (37.18)
    College or higher184 (42.59)300 (54.95)
    Missing21
Family history of cancer0.71
    No345 (79.49)440 (80.44)
    Yes89 (20.51)107 (19.56)
Family history of HNSCC
    No422 (97.24)535 (97.81)0.57
    Yes12 (2.76)12 (2.19)
First-degree relative with cancer0.96
    No360 (82.95)453 (82.82)
    1-261 (14.06)79 (14.44)
    ≥313 (3)15 (2.74)
Pack-years of tobacco use<0.001
    None78 (17.97)182 (33.27)
    >0 to <2083 (19.12)152 (27.79)
    20 to <45116 (26.73)121 (22.12)
    ≥45157 (36.18)92 (16.82)
Alcohol consumption, average drinks per week<.001
    <370 (16.43)139 (25.6)
    3 to <889 (20.89)176 (32.41)
    8 to <25101 (23.71)147 (27.07)
    ≥25166 (38.97)81 (14.92)
    Missing84
HPV 16<0.001
    Negative300 (69.12)489 (89.4)
    Positive134 (30.88)58 (10.6)
Tumor sites
    Oral160 (36.87)
    Pharynx190 (43.78)
    Larynx84 (19.35)