Table 1.

Final body, fat pad weights, and MT characteristic for AL, CCR, and ICR TGF-α female mice

AL (n = 69)CCR (n = 65)ICR (n = 59)
ICR-Refed (n = 29)ICR-Restricted (n = 30)
Final body weight (g)33.79 ± 0.71*27.19 ± 0.3627.38 ± 0.5024.27 ± 0.50
Mammary fad pad weight, g (combined right and left mammary fat pads)1.77 ± 0.11*0.87 ± 0.040.86 ± 0.070.35 ± 0.06
Internal fat pad weight, g (combined parametrial and retroperitoneal fat pads)2.27 ± 1.37*0.93 ± 0.47*1.01 ± 0.0.080.48 ± 0.03
AL (n = 69)CCR (n = 65)ICR (n = 66)
Age of MT detection (wk)61.0 ± 1.1*69.0 ± 1.667.0 ± 4.2*
% of mice in group with MT (number with MT/total mice)71.0% (69/49)*35.4% (65/23)9.1% (66/6)
MT weight (g)0.93 ± 0.110.43 ± 0.040.66 ± 0.38
No. MTs/mouse (average in tumor-bearing mice)1.82 ± 0.17*1.39 ± 0.181.00
Total (no. MTs)89326
    Low grade and a carcinoma in situ (number/%)5/5.6%2/6.3%1/16.7%
    Grade 2 (number/%)76/84.3%27/84.3%4/66.6%
    Grade 3 (number/%)9/10.1%3/9.4%1/16.7%

NOTE: Values are mean ± SE.

  • *Values within a column with different superscript symbol are significantly different by χ2 analysis.