Table 2

Observed and estimated numbers and proportions of prostate cancer detected on biopsy

Placebo armFinasteride armRR (95% CI)P-value
n= 8,024n= 7,966
Prostate cancer
 Estimate of overall prevalence1,693 (21.1%)1,171 (14.7%)0.70 (0.64-0.76)<0.0001
 Observed1,194 (22.9%)823 (16.6%)0.72 (0.67-0.79)<0.0001
High-grade cancer
 Estimate of overall prevalence337 (4.2%)382 (4.8%)1.14 (0.96-1.35)0.12
 Observed252 (4.8%)288 (5.8%)1.21 (1.02-1.42)0.02