Table 1

Time-dependent effects of TS on gene expression in MSK-Leuk1 cells

Gene nameAffymetrix ID0.5 h3 h6 h12 h24 hDescription
FoldPFoldPFoldPFoldPFoldP
CYP1A1205749_at13.43.3e−0617.42.1e−0823.41.1e−0711.31.5e−0614.31.0e−05Cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1202437_s_at8.34.2e−0614.14.0e−0613.51.7e−065.85.5e−066.12.1e−08Cytochrome P450, family 1, subfamily B, polypeptide 1
CYP1B1202435_s_at8.13.8e−0611.41.2e−0612.11.7e−066.74.3e−056.11.2e−04Cytochrome P450, family 1, subfamily B, polypeptide 1
CYP1B1202436_s_at7.44.3e−0611.04.5e−0511.25.5e−086.01.5e−065.91.7e−04Cytochrome P450, family 1, subfamily B, polypeptide 1
IL24206569_at2.85.8e−043.44.0e−062.83.6e−043.77.9e−042.81.7e−03Interleukin-24
PTGS21554997_a_at2.77.0e−033.01.0e−033.04.0e−033.12.3e−033.04.8e−04Prostaglandin-endoperoxide synthase 2 (COX-2)
EREG205767_at2.11.8e−032.64.0e−062.23.8e−052.48.2e−052.01.0e−04Epiregulin
LOC1514381560679_at2.18.7e−031.91.4e−021.53.7e−023.22.1e−025.96.8e−05Hypothetical protein LOC151438
PTGS2204748_at2.11.2e−042.71.6e−042.42.6e−033.26.1e−042.91.5e−04Prostaglandin-endoperoxide synthase 2 (COX-2)
TIPARP212665_at2.02.2e−063.09.3e−092.21.7e−062.21.5e−062.01.0e−04TCDD-inducible poly(ADP-ribose) polymerase
IL1B205067_at1.91.3e−042.23.5e−072.13.1e−062.15.5e−062.16.4e−05Interleukin-1β
ALDH1A3203180_at1.91.9e−042.09.8e−092.42.8e−062.01.3e−032.82.8e−04Aldehyde dehydrogenase 1 family, member A3
IL1R2211372_s_at1.98.4e−061.71.9e−021.95.6e−042.92.2e−035.04.6e−04Interleukin-1 receptor, type II
IL1R2205403_at1.81.1e−051.61.6e−021.85.2e−032.73.8e−035.36.6e−04Interleukin-1 receptor, type II
IL1B39402_at1.82.9e−052.12.1e−082.01.7e−061.95.5e−062.29.4e−05Interleukin-1β
IL20224071_at1.78.3e−032.16.4e−051.84.6e−041.71.5e−021.72.7e−03Interleukin-20
DUSP4204014_at1.71.3e−021.62.5e−031.71.2e−042.32.3e−042.45.4e−04dual specificity phosphatase 4
226034_at1.68.6e−031.62.6e−041.53.4e−042.12.4e−032.04.4e−04Clone IMAGE:3881549, mRNA
SERPINB2204614_at1.62.9e−031.65.8e−041.62.4e−041.91.8e−042.51.0e−05Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
LOC344887241418_at1.55.0e−023.62.9e−054.25.5e−082.68.8e−051.99.8e−04Similar to NmrA-like family domain containing 1
MAF209348_s_at−1.51.9e−04−1.52.7e−02−1.51.8e−02−1.72.1e−02−1.81.7e−03v-maf musculoaponeurotic fibrosarcoma oncogene homologue (avian)
PRICKLE1226069_at−1.64.1e−02−1.61.2e−02−2.22.0e−03−1.62.8e−02−2.07.7e−04Prickle homologue 1 (Drosophila)
NAV2218330_s_at−1.73.8e−03−1.81.3e−02−1.72.0e−03−1.73.7e−03−1.81.0e−04Neuron navigator 2
FILIP1L204135_at−1.73.8e−06−2.17.1e−06−2.21.3e−05−2.41.9e−03−2.16.4e−05Filamin A interacting protein 1-like
FILIP1L1554966_a_at−1.78.4e−06−2.26.4e−05−2.22.0e−06−2.51.5e−03−2.21.0e−04Filamin A interactiong protein 1-like
C10orf10209183_s_at−2.06.1e−04−2.31.2e−03−2.14.4e−05−2.34.3e−05−2.16.4e−05Chromosome 10 open reading frame 10
TNFSF10202688_at−2.08.7e−03−1.71.3e−02−2.44.2e−03−2.34.8e−04−2.41.9e−04Tumor necrosis factor (ligand) superfamily, member 10

NOTE: Fold-differences and P values are shown at each time point. Detailed lists and annotations are provided at http://physiology.med.cornell.edu/go/smoke.