Table 3

Weight distribution, food consumption, and serum IGF-I levels of ICR female mice maintained on control, high-fat, normal, and lean diet regimens (eight mice per group)

Experimental dietMass, start of study (g)Mass, end of study (g)Average food consumption (g)Serum IGF-I, end of study (ng/mL)
10 kcal% fat30.8 ± 0.5040.3 ± 1.06a25.6 ± 0.3a786 ± 86.26a
60 kcal% fat32.2 ± 0.5655.9 ± 1.28b31.5 ± 0.4b917 ± 84.19a
15% CR30.9 ± 1.0734.9 ± 0.84c21.5 ± 0.2c542 ± 88.31b
30% CR30.8 ± 0.6623.3 ± 0.52d18.1 ± 0.2d311 ± 42.5c

NOTE: The data represent mean ± SE. Superscript letters indicate that values are significantly different from each other.