Table 3

Correlation between oral methylation status and bronchial methylation index

Bronchial methylation index
OralnMean ± SD, median (range)P*
Baseline
p16U1000.18 ± 0.22, 0.17 (0-0.83)<0.0001
M240.47 ± 0.30, 0.50 (0-1.00)
FHITU1050.10 ± 0.20, 0.00 (0-1.00)<0.0001
M190.50 ± 0.29, 0.50 (0-1.00)
p16/FHITU860.27 ± 0.26, 0.17 (0-1.00)<0.0001
M390.53 ± 0.29, 0.50 (0-1.00)
3 mo
p16U890.14 ± 0.21, 0.00 (0-1.00)<0.0001
M360.39 ± 0.29, 0.33 (0-1.00)
FHITU1130.08 ± 0.18, 0.00 (0-1.00)<0.0001
M140.57 ± 0.28, 0.67 (0.17-1.00)
p16/FHITU830.21 ± 0.24, 0.17 (0-1.00)<0.0001
M440.50 ± 0.31, 0.50 (0-1.00)
  • *Wilcoxon's rank-sum test comparing bronchial brush methylation index between oral brush methylation groups.