Table 2

Weight distribution, food consumption, and serum IGF-I levels of C57BL/6 male mice maintained on control, high-fat, and lean diet regimens (10 mice per group)

Experimental dietMass, start of study (g)Mass, end of study (g)Average food consumption (g)Serum IGF-I, end of study (ng/mL)
10 kcal% fat17.3 ± 0.337.5 ± 0.8a23.3 ± 0.43a615 ± 52.25a
60 kcal% fat17.7 ± 0.347.0 ± 0.8b22.9 ± 0.88a987 ± 92.53b
30% CR16.9 ± 0.421.1 ± 0.3c16.2 ± 0.37b208 ± 32.38c

NOTE: The data represent mean ± SE. Superscript letters indicate that values are significantly different from each other.