Table 3.

Mean size of largest polyp by intervention group at baseline and at the end of intervention with aspirin (A) and/or RS

 Mean Size of largest polypa (N)
Four intervention group comparisonbAspirin comparisonStarch comparison
RSP/APcRS/APA/RSPA/RSNonaspirincAspirinNon-RScRS
At baselined6.9 (31)4.3 (20)4.0 (25)4.6 (19)5.8 (51)4.3 (44)5.6 (56)4.4 (39)
P0.120.070.410.310.55
Final largest polyp size for all patientse6.5 (31)4.0 (20)3.4 (25)4.4 (19)5.5 (51)3.8 (44)5.1 (56)4.2 (39)
P0.030.0060.070.050.27
P adjusted for baseline0.100.030.110.090.35
Final largest polyp size for patients treated for more than 1 year6.5 (17)4.6 (7)2.9 (8)3.1 (9)6.0 (24)3.0 (17)5.4 (25)3.8 (16)
P0.260.030.020.010.17
P adjusted for baseline0.420.090.030.020.19

Abbreviations: AP, aspirin placebo; RSP, RS placebo.

  • aRaw means presented, log-transformed measures used in tests.

  • bThe P values are from linear regression for the following comparisons: RS/P versus P/P, A/P versus P/P, and A/RS versus P/P.

  • cReference group in the linear regression models.

  • dOf 133 patients, 23 did not have polyps measured at baseline and 15 did not have polyps measured throughout the study. Numbers are based on patients who also have a result postbaseline.

  • eNumbers are based on patients who also have a baseline result.