Table 5.

Associations between total deaths and postdiagnosis moderate- to vigorous-intensity physical activity stratified by demographic and prognostic variables

 Postdiagnosis moderate-vigorous intensity physical activity, MET-h/wk
0>0
Full sample
 Total deaths/total women83/907103/2,003
 Multivariable HR (95% CI)21.00 0.58 (0.42–0.79)
BMI < 25 kg/m2
 Total deaths/total women20/20144/780
 Multivariable HR (95% CI)1.00 0.49 (0.270.91)
BMI = 25–29.9 kg/m2
 Total deaths/total women28/30527/696
 Multivariable HR (95% CI)1.00 0.43 (0.240.76)
BMI ≥ 30 kg/m2
 Total deaths/total women32/39331/512
 Multivariable HR (95% CI)1.000.80 (0.45–1.41)
Stage I
 Total deaths/total women43/65460/1,535
 Multivariable HR (95% CI)1.00 0.65 (0.420.99)
Stage II–IIIA
 Total Deaths/Total Women33/23436/423
 Multivariable HR (95% CI)1.00 0.46 (0.270.78)
ER-negative
 Total deaths/total women14/12323/255
 Multivariable HR (95% CI)1.000.78 (0.35–1.73)
ER-positive
 Total deaths/total women57/68864/1,530
 Multivariable HR (95% CI)1.00 0.50 (0.340.74)
HER2-positive
 Total deaths/total women7/979/202
 Multivariable HR (95% CI)1.000.71 (0.16–3.11)
HER2-negative
 Total deaths/total women21/36919/782
 Multivariable HR (95% CI)1.00 0.37 (0.19–0.75)

NOTE: Physical activity assessed at visit closest to diagnosis (i.e., either year 3 or year 6). Adjusted for age, stage, ER, PR, grade, her2, ethnicity, WHI study arm, previous hormone therapy use, time from diagnosis to physical activity assessment, BMI, diabetes, alcohol, smoke, total calories, and percentage calories from fat, and servings of fruit and vegetables. P = 0.63, 0.13, 0.79, and 0.40 for interaction between BMI, stage, ER status, and her2 status, respectively.