AE listings deemed to be possibly or probably related to SRT501/placebo intervention
| SRT501 (N = 6) | Placebo (N = 3) | |||
|---|---|---|---|---|
| AE | No. of events | No. of patients | No. of events | No. of patients |
| GI disorders | 12 | 5 | 2 | 1 |
| Anal pruritus | 1 | 1 | 0 | 0 |
| Diarrhea | 7 | 5 | 2 | 1 |
| Nausea | 4 | 1 | 0 | 0 |
| General disorders | 1 | 1 | 0 | 0 |
| Chills | 1 | 1 | 0 | 0 |
| Nervous system disorders | 1 | 1 | 1 | 1 |
| Lethargy | 0 | 0 | 1 | 1 |
| Peripheral neuropathy | 1 | 1 | 0 | 0 |
| Skin/tissue disorders | 2 | 2 | 0 | 0 |
| Rash | 1 | 1 | 0 | 0 |
| Skin irritation | 1 | 1 | 0 | 0 |
| Vascular disorders | 1 | 1 | 0 | 0 |
| Flushing | 1 | 1 | 0 | 0 |