Table 2.

Geometric mean and 5th and 95th percentile ranges of case and control subjects, the EPIC cohort, 2007

HormonesCasesControlsPdiffa
Study phase 1n = 329n = 596
 Estradiol (pmol/L)97.26 (50.39–209.74)88.63 (43.78–189.41)0.001
 Free estradiol (pmol/L)2.53 (1.26–6.13)2.27 (1.01–5.01)0.001
 Testosterone (nmol/L)1.25 (0.52–2.85)1.08 (0.38–2.64)0.0002
 Free testosterone (pmol/L)20.31 (7.92–57.26)17.12 (4.60–49.02)0.0002
 SHBG (nmol/L)34.26 (15.41–77.23)35.15 (12.56–86.91)0.46
Study phase 2n = 225n = 225
 Estradiol (pmol/L)46.02 (26.31–140.27)40.66 (25.91–79.27)0.003
 Free estradiol (pmol/L)1.08 (0.56–3.62)0.93 (0.52–1.92)0.001
 Testosterone (nmol/L)1.39 (0.56–3.16)1.18 (0.52–2.60)0.0001
 Free testosterone (pmol/L)18.89 (7.11–51.23)14.80 (5.90–37.64)<0.0001
 SHBG (nmol/L)45.67 (18.68–105.0)51.69 (22.99–112.8)0.01
  • aP for difference from paired t test.