Table 1.

Age-adjusted characteristics of adenomatous and hyperplastic polyp cases and controls

CharacteristicControls (N = 3,431)Adenomatous (n = 1,529)Hyperplastic (n = 499)Pa
Age (y, mean ± SD)56.8 ± 7.758.8 ± 7.356.7 ± 7.0<0.0001
Sex (female, %)43.927.531.0<0.0001
Race (%)
Caucasian87.586.090.9
African American10.511.78.0
Other2.02.31.10.05
Smoking (%)
Current12.728.333.8
Former35.136.538.1
Never52.235.228.1<0.0001
Alcohol consumption (%)
Current18.421.123.4
Former22.429.327.4
Never59.349.749.2<0.0001
Family history of colon cancer or adenomatous polyp (yes, %)14.616.614.70.17
Educational attainment (%)
High school or less24.333.233.7
Some college28.429.230.1
College graduate20.719.818.6
Graduate or professional education26.617.917.6<0.0001
Regularly exercised (%)57.849.854.4<0.0001
BMI (kg/m2, mean ± SD)28.1 ± 5.828.9 ± 5.728.8 ± 5.9<0.0001
Use of HRT (ever, %)b59.662.860.50.72
Study site (%)
Academic center72.758.855.5
VA27.341.244.5<0.0001
Indication for colonoscopy (%)
Screening70.567.664.6
Diagnostic/bleeding/other29.532.435.40.01
  • aANOVA for continuous variables and χ2 test for categorical.

  • bWomen only (n = 2,082).