Table 3.

Logistic-regression models fitted on the training set to screen for SCC at the upper aerodigestive tract based on the combination of traditional risk factors and epigenetic markers

Multivariate analyses with model selection
Risk factorsAdjusted OR95% CIP
Models based on both traditional risk factors and epigenetic markers
 Exposure to at least one of ABC4.5571.141–18.2080.032
 Presence of numerous LVLs in the background mucosae8.4282.458–28.903<0.001
HOXA9 methylation level (%)1.1181.039–1.2040.003
NEFH methylation level (%)1.3501.042–1.7490.023