Table 1.

Characteristics of breast cancer patients by antiestrogen therapy use, Geneva Cancer Registry, 1980 to 2005

Antiestrogen use
No (n = 4,002)Yes (n = 3,358)
Number%Number%P
Period of cancer diagnosis<0.001
 1980–19902,06351.541712.4
 1991–20051,93948.52,94187.6
Age at diagnosis, y<0.001
 <402636.61003.0
 40–4985121.342412.6
 50–5998924.783825.0
 60–6978619.686425.7
 70–7967316.863719.0
 ≥8044011.049514.7
Civil status<0.001
 Single54713.745913.7
 Married2,15853.91,64449.0
 Widowed73118.375922.6
 Separated56614.149614.8
Social class0.084
 Low93626.074225.1
 Middle2,01155.81,72358.4
 High65418.248616.5
Familial risk of breast/ovary cancera0.043
 Low1,33773.81,99170.8
 Moderate37620.863022.4
 High985.41926.8
Familial history of melanomaa0.208
 None2,09999.12,95698.6
 First relatives120.6301.0
 Second relatives60.3110.4
Stage0.034
 I1,36634.11,23136.7
 II1,69342.31,44443.0
 III45311.333510.0
 IV2265.62286.8
Histologic subtype<0.001
 Ductal3,10479.42,49075.9
 Lobular2747.040812.4
 Others53113.638311.7
Differentiation<0.001
 Good54722.591132.7
 Moderate1,10445.41,39350.0
 Poor78232.148117.3
Diameter0.418
 1–20 mm2,40565.42,02866.8
 21–40 mm1,02427.980226.4
 >40 mm2466.72046.7
Estrogen receptor statusb<0.001
 Positive69158.82,24297.1
 Negative48541.2682.9
Progesterone receptor statusb<0.001
 Positive55146.81,83979.5
 Negative62653.247420.5
Radiotherapy<0.001
 No1,98249.51,07332.0
 Yes2,02050.52,28568.0
Surgery<0.001
 No42510.649514.7
 Yes3,57789.42,86385.3
Chemotherapy0.001
 No2,59164.72,29068.2
 Yes1,41135.31,06831.8

Numbers may not sum to 100% because of rounding and missing data.

  • aRecorded since 1990.

  • bRecorded since 1995.