Table 1.

Three putative EZH2 target genes identified by genome-wide approaches selected for further validation

Gene nameLocationFunction% TCGA cases downregulated >2-fold
NM_000689 ALDH1A19q21.13Cancer stem cell marker96
NM_001049 SSTR114q13Proliferation and invasion inhibitor, cell signaling95
NM_145056 DACT319q13.32Apoptosis inducer, Wnt signaling antagonist76