Table 2.

Percentage of inflammatory and ulcerative lesions and of precancerous and cancerous lesions in mice treated with AOM/DSS ± AG ± hexane fraction of AG (Hex-AG) at day 50

Day 50: analysis of inflammatory and ulcerative lesions
No of animalsTotal no. of inflammatory/Inflammatory lesions
Groupulcerative lesionsMildSevereUlcerative mucosa
PBS102218.2%54.5%27.3%
AGa914c50%50%0%
Hex-AGb1017c76.6%17.6%5.8%
Day 50: analysis of precancerous and cancerous lesions
No. of animalsTotal no. of precancerous/PolypsNoninvasive adenomasInvasive
Groupcancerous lesionsLow-grade dysplasiaHigh-grade dysplasiaadenocarcinoma
PBS10270%67%26%7%
AG918d0%83%11.5%5.5%
Hex-AG10258%83%4%0%

Abbreviation: AG, American ginseng.

  • aWhole American ginseng extract.

  • bHexane fraction of American ginseng.

  • cSignificant decrease compared with the control (PBS) treated group (P < 0.05).

  • dSignificant decrease compared with the control (PBS) treated group (P < 0.05).