Table 1.

Percentage of inflammatory and ulcerative lesions and of precancerous and cancerous lesions in mice treated with AOM/DSS ± AG ± hexane fraction of AG (Hex-AG) at days 35

Day 35: analysis of inflammatory and ulcerative lesions
No. ofTotal no. of inflammatory/Inflammatory lesions
Groupanimalsulcerative lesionsMildSevereUlcerative mucosa
PBS44445.4%18.2%36.4%
AGa424c62.5%20.8%16.7%
Hex-AGb428c71.4%21.4%7.2%
Day 35: analysis of precancerous and cancerous lesions
No. ofTotal no. of precancerous/Noninvasive adenomasInvasive
Groupanimalscancerous lesionsPolypsLow-grade dysplasiaHigh-grade dysplasiaadenocarcinoma
PBS4110%9%82%9%
AG41d0%100%0%0%
Hex-AG40d0%0%0%0%

Abbreviation: AG, American ginseng.

  • aWhole American ginseng extract.

  • bHexane fraction of American ginseng.

  • cSignificant decrease compared with the control (PBS) treated group (P < 0.05).

  • dSignificant decrease compared with the control (PBS) treated group (P < 0.05).