Table 3.

Tumor characteristics, treatment, and mammography screening detection in relation to adherence for patients with ER-positive tumors who had been advised to take endocrine treatment

Total number of patients, 1-y follow-up (%), N = 417Adherent, 1-y follow-up (%), N = 381Nonadherent, 1-y follow-up (%), N = 36RR (95% CI)PTotal number of patients, 2-y follow-up (%), N = 339Adherent, 2-y follow-up (%), N = 306Nonadherent, 2-y follow-up (%), N = 33RR (95% CI)P
pT
In situ1 (0.2)1 (100)01 (0.3)1 (100)0
 I282 (67.6)251 (89.1)31 (10.9)2.94 (1.17–7.38)0.014234 (69.0)207 (88.5)27 (11.5)1.99 (0.85–4.68)0.10
 II125 (30.0)120 (96.0)5 (4.0)97 (28.6)92 (94.8)5 (5.2)
 III8 (1.9)8 (100)016 (1.8)5 (83.3)1 (16.7)1
 IV1 (0.2)1 (100)01 (0.3)1 (100)0
 Missing000000
Histologic grade
 I82 (19.7)65 (79.3)17 (20.7)3.66 (1.99–6.71)<0.000169 (20.4)53 (76.8)16 (23.2)3.68 (1.96–6.91)<0.0001
 II260 (62.4)244 (93.8)16 (6.2)222 (65.5)205 (92.3)17 (7.7)
 III75 (18.0)72 (96.0)3 (4.0)148 (14.2)48 (100)01
 Missing000000
Nodal involvement
 0 positive nodes219 (52.6)195 (89.0)24 (11.0)1.80 (0.92–3.50)0.078177 (52.4)155 (87.6)22 (12.4)1.82 (0.91–3.63)0.083
 1–3 positive nodes151 (36.3)142 (94.0)9 (6.0)127 (37.6)116 (91.3)11 (8.7)
 ≥4 positive nodes46 (11.1)43 (93.5)3 (6.5)134 (10.1)34 (100)01
 Missing110110
PR status
 PR-positive328 (78.7)297 (90.5)31 (9.5)1.68 (0.67–4.20)0.25265 (78.2)237 (89.4)28 (10.6)1.56 (0.63–3.91)0.33
 PR-negative89 (21.3)84 (94.4)5 (5.6)174 (21.8)69 (93.2)5 (6.8)1
 Missing000000
Type of surgery
 MRM193 (46.3)184 (95.3)9 (4.7)1147 (43.4)137 (93.2)10 (6.8)1
 BCS224 (53.7)197 (87.9)27 (12.1)2.58 (1.25–5.36)0.007192 (56.6)169 (88.0)23 (12.0)1.76 (0.87–3.58)0.11
 Missing000000
Mammography detecteda
 Yes219 (57.9)197 (90.0)22 (10.0)1.60 (0.78–3.28)0.20182 (58.3)162 (89.0)20 (11.0)1.41 (0.68–2.90)0.35
 No159 (42.1)149 (93.7)10 (6.3)1128 (41.3)118 (92.2)10 (7.8)1
 Missing000000
Chemotherapy
 Yes71 (17.0)70 (99.0)1 (1.0)148 (14.2)48 (100)01
 No346 (83.0)311 (89.9)35 (10.1)7.18 (1.00–51.6)0.017291 (85.8)258 (88.7)33 (11.3)1.12 (1.08–1.18)0.014
 Missing000000
Radiotherapy
 Yes254 (60.9)229 (90.2)25 (9.8)1.46 (0.74–2.88)0.27210 (61.9)190 (90.5)20 (9.5)0.94 (0.49–1.83)0.87
 No163 (39.1)152 (93.3)11 (6.7)1129 (38.1)116 (89.9)13 (10.1)1
 Missing000000

Abbreviations: BCS, breast-conserving surgery; MRM, modified radical mastectomy,

  • aWomen younger than 45 (n = 39 and n = 29 for the 1- and 2-year follow-up, respectively) were excluded as women previously started mammography at age of 45 years in Lund.