Table 4.

Univariate and multivariate analyses of predictors of HCC occurrence in patients with viral C cirrhosis with OV (n = 93)

Univariate analysisMultivariate analysis
VariablesHR (95% CI)PHR (95% CI)P
Age1 (0.96–1.04)0.91
BMI1.1 (1.02–1.19)0.014
Male sex2.6 (1–6.79)0.050
Mixed etiology0.92 (0.35–2.41)0.86
Diabetes0.99 (0.39–2.48)0.99
AFP1 (0.96–1.03)0.76
Prothrombin activity1 (0.97–1.03)0.99
Albumin1.01 (0.93–1.1)0.76
Bilirubin0.98 (0.95–1.02)0.38
Platelet count1 (0.99–1.01)0.81
ALT0.97 (0.72–1.3)0.82
AST0.5 (0.25–1)0.051
Alkaline phosphatase0.96 (0.41–2.25)0.93
GGT0.98 (0.84–1.14)0.78
Child–Pugh B0.22 (0.01–3.92)0.30
Propranolol treatment0.16 (0.06–0.45)0.00050.16 (0.06–0.45)0.0005

NOTE: Mixed etiology for past or ongoing daily alcohol intake >30 g/d.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase.