Table 1.

Prevalence and RR estimates used in the YDR calculation

Risk factoraRR multiplierePrevalencee
Body mass index
 Men ≤ 301.065%
 Men > 301.535%
 Women ≤ 301.060%
 Women > 301.540%
 Men ≤ 5′10″1.060%
 Men > 5′10″1.340%
 Women ≤ 5′7″1.090%
 Women > 5′7″1.310%
Aspirin use, most days >15 y
 Men, no1.089%
 Men, yes0.711%
 Women, no1.087%
 Women, yes0.713%
Duration of birth control pill use
 Never/<5 y1.080%
 ≥5 y0.720%
Duration of hormone replacement therapy
 Never/<5 y1.092.5%
 ≥5 y0.87.5%
Red meat intake, ≥3 servings/wk
Servings of alcohol on a typical day
 Men < 21.095%
 Men ≥ 21.45%
 Women < 21.098%
 Women ≥ 21.42%
Multivitamin use ≥4 d/wk
Calcium sufficiencyb
Daily vitamin D supplement ± calciumc
Moderate physical activity ≥30 min daily
Parent or sibling with CRC
Prior screeningd
  • aItems related to age, sex, and previous cancer are not included in the risk calculation.

  • bThe RR calculation uses a calcium “sufficient” variable defined by daily use of a calcium supplement or daily intake of ≥3 servings of milk/dairy.

  • cThe vitamin D group includes patients who either a took vitamin D supplement alone or a multivitamin on most days.

  • dPrior screening defined as a colonoscopy within 10 years, flexible sigmoidoscopy or barium enema within 5 years, or fecal occult blood testing within 1 year.

  • eThe RR multiplier (RRIn) for the numerator of the formula depends on whether the risk factor is present or absent; the multiplier for the denominator (RRCn) is the population-based RR estimate. Citations for the RR multiplier and prevalence estimates can be accessed at (11).