Table 2.

ROC analysis of the ability of RASGRF1 methylation to discriminate between patients with gastric cancer and healthy individuals

AUCSensitivitySpecificity
Estimate95% confidence interval (CI)Cut-offEstimate95% CIEstimate95% CI
Total (n = 161)0.821(0.775%–0.887%)7.71%78.02%(68.12%–86.03%)75.36%(63.51%–84.94%)
11.68%74.73%(64.53%–83.25%)84.06%(73.26%–91.76%)
12.76%70.33%(59.84%–79.45%)86.96%(86.68%–93.86%)
PG-positive (n = 35)0.763(0.601%–0.926%)6.79%80.00%(56.34%–94.27%)60.00%(32.29%–83.66%)
13.67%70.00%(45.72%–88.11%)86.67%(59.54%–98.34%)
22.29%55.00%(31.53%–76.94%)93.33%(68.05%–99.83%)
PG-negative (n = 41)0.844(0.719%–0.969%)7.13%77.78%(52.36%–93.59%)73.91%(51.60%–89.77%)
10.64%72.22%(46.52%–90.31%)86.96%(66.41%–97.22%)
13.39%6.67%(40.99%–86.66%)91.30%(71.96%–98.93%)