Table 2.

MiRNAs and pharmaceuticals in cancer chemoprevention

PharmaceuticalsModelsUpregulationDownregulationRef
Estrogen receptor antagonist
 TamoxifenHuman breast cancer cellsmiR-221, miR-222(75, 76)
Human breast cancer cellsmiR-342(77)
 FulvestrantHuman breast cancer cellsmiR-221, miR-222(79)
NSAIDs
 CelecoxibHuman gastric cancer cellsmiR-29c(84)
 SulindacHuman colon and breast cancer cellsmiR-10b, miR-17, miR-21, miR-9(85)