Table 5.

Median relative percent change in biomarkers, by study arm

OverallPlaceboDrug
ARM: MARKERMedian95% CIMedian95% CIMedian95%CI
Buccal-Cell−8.9−24.5−4.2−33.6−10.1−52.3
NeuN = 45+18.5N = 24+36.7N = 21+24.6
Protease+16.2−10.0+17.2−10.3+15.7−23.8
ActivityN = 45+27.0N = 24+30.9N = 21+74.9
Serum−4.1−11.3−8.1−15.3−3.9−13.5
NeuN = 41+0.7N = 22+6.6N = 19+8.1