Table 2.

Raloxifene metabolite profiles in plasma from subjects treated with raloxifene

Treatment groupral-4′-Gluc (ng/mL plasma)ral-6-Gluc (ng/mL plasma)ral-4′-Gluc/ral-6-GlucRaloxifene (ng/mL plasma)Total ral-Gluc/raloxifene
Raloxifene 30 mg (n = 39)22 (2.7–95)6.3 (0–26)3.30.28 (0.12–0.58)114
Raloxifene 60 mg (n = 42)50 (5.9–188)15 (2.6–59)3.80.58 (0.18–2.3)133