Table 3.

Difference in percent mammographic density (95% CI) by metabolic syndrome status and components of metabolic syndrome among postmenopausal women stratified by state (ESMaestras, 2006)

Jalisco (N = 142)Veracruz (N = 180)
n (%) exposedAge-adjustedaMV-adjustedbMV-adjusted with BMIcn (%) exposedAge-adjustedaMV-adjustedbMV-adjusted with BMIc
Metabolic syndrome
Harmonized definition (waist ≥ 88 cm)73 (51.4)−2.60 (−7.32 to 2.12)−2.87 (−8.31 to 2.58)−0.62 (−6.76 to 5.53)70 (38.9)−3.68 (−7.56 to 0.20)−2.70 (−6.89 to 1.48)−1.63 (−5.97 to 2.71)
Harmonized definition (waist ≥ 80 cm)85 (59.9)1.64 (−3.18 to 6.46)1.79 (−3.62 to 7.2)3.98 (−1.71 to 9.68)80 (44.4)−4.69* (−8.51 to −0.86)−3.45 (−7.61 to 0.71)−2.71 (−6.93 to 1.51)
Individual metabolic syndrome components
Abdominal obesity (waist ≥ 88 cm)98 (69.0)−7.50* (−12.45 to −2.54)−6.61* (−12.47 to −0.74)−5.03 (−11.92 to 1.86)110 (61.1)−6.33* (−10.09 to −2.58)−5.55* (−9.67 to −1.44)−4.69 (−9.70 to 0.33)
 Abdominal obesity (waist ≥ 80 cm)129 (90.9)−3.14 (−11.29 to 5.01)−0.76 (−9.91 to 8.39)2.11 (−7.50 to 11.71)160 (88.9)−6.13* (−12.06 to −0.2)−3.28 (−9.69 to 3.12)−0.83 (−7.79 to 6.13)
High fasting triglycerides (≥150 mg/dL)77 (54.2)0.67 (−4.06 to 5.39)−1.14 (−6.69 to 4.41)0.64 (−5.10 to 6.38)61 (33.9)0.38 (−3.62 to 4.38)0.63 (−3.73 to 4.99)0.92 (−3.41 to 5.25)
Low HDL (<50 mg/dL)93 (65.5)0.66 (−4.29 to 5.61)0.87 (−5.01 to 6.75)2.57 (−3.55 to 8.70)77 (42.8)1.57 (−2.23 to 5.38)3.42 (−0.72 to 7.56)3.49 (−0.61 to 7.58)
High blood pressure (SBP ≥ 130 mmHg or DBP ≥ 85 mmHg)73 (51.4)−0.89 (−5.63 to 3.85)−0.06 (−5.81 to 5.69)2.01 (−4.06 to 8.07)81 (45.0)−1.02 (−4.96 to 2.92)−0.03 (−4.34 to 4.28)0.81 (−3.54 to 5.15)
High fasting glucose (≥100 mg/dL)40 (28.2)−3.87 (−9.14 to 1.40)−3.55 (−10.04 to 2.93)−2.66 (−9.37 to 4.05)50 (27.8)−3.72 (−7.92 to 0.47)−2.11 (−6.69 to 2.47)−1.53 (−6.11 to 3.05)
 High fasting glucose (≥110 mg/dL)24 (16.9)−3.56 (−9.85 to 2.73)−3.93 (−11.53 to 3.67)−2.23 (−10.13 to 5.67)28 (15.6)−4.60 (−9.76 to 0.55)−3.99 (−9.54 to 1.56)−3.89 (−9.38 to 1.61)
  • aModel 1: adjusted for age at mammogram (continuous).

  • bModel 2: Model 1 and family history of breast cancer (yes, no), history of BBD (yes, no), age at menarche (<12, 12, 13, 14+, unknown), oral contraceptive use (never, ever < 5, ever 5+), number of full-term pregnancies (nulliparous, 1, 2, 3, 4+), age at first pregnancy (nulliparous, <20, 20–24, 25–29, 30+), alcohol intake (none, <0.1, 0.1–0.2, 0.2+ drinks/d), smoking status (never, ever), age at menopause (<40, 40–44, 45–49, 50+, unknown), and SES (low, medium, high).

  • cModel 3: Model 2 and BMI at mammogram (continuous).

  • *P < 0.05.