Table 1.

Patient characteristics

Compliant-to-treatment sample
All (N = 70)Zileuton (n = 52)Zileuton + celecoxib (n = 18)P
Age, y
 Mean ± SD43.6 ± 9.143.8 ± 9.643.1 ± 7.60.76
Gender0.58
 Female27 (39%)19 (37%)8 (44%)
 Male43 (61%)33 (63%)10 (56%)
Race, n (%)0.07
 Asian2 (3%)0 (0%)2 (11%)
 Black35 (50%)28 (54%)7 (39%)
 White33 (47%)24 (46%)9 (50%)
Smoking (pack-years)
 Median (range)19.5 (10–68)19.5 (10–68)19.5 (10–40)0.59
Baseline PGE-M, ng/mg Cr
 Median (range)12.6 (1.4–50.4)12.8 (1.4–50.4)10.2 (2.3–35.1)0.61
Baseline LTE4, pg/mg Cr
 Median (range)102.5 (4–268)107 (4–268)86.5 (37–250)0.42