Table 1.

Measurements of circulating metabolic parameters, food consumption, and weights in grouped versus isolated TAg female mice

GroupedIsolatedP-value
Blood glucose (mg/dL)113.4 ± 9.85110.4 ± 3.540.79
Serum Insulin (pg/mL)361.5 ± 78.8349.3 ± 82.80.92
NEFA (mEq/L)0.93 ± 0.100.79 ± 0.070.24
Serum Leptin (ng/mL)1.36 ± 0.391.31 ± 0.550.94
Serum Cort. (ng/mL)76.8 ± 37.067.9 ± 39.30.66
Food consumption: 8–10 weeks (kcal/day)9.33 ± 0.3610.60 ± 0.260.03
Food consumption: 11–17 weeks (kcal/day)10.47 ± 0.3512.58 ± 0.350.002
Weight: age 10 weeks (g)18.9 ± 0.4818.8 ± 0.230.85
Weight: age 17 weeks (g)21.2 ± 0.4721.4 ± 0.540.81

NOTE: Circulating markers were obtained from 15-week-old animals (9 group housed, 8 isolated). Food consumption and weights (16 group housed, 15 isolated) are divided into pre- and posttumor time periods to investigate the effects of tumor burden on metabolism. Data indicate means ± SD, with P value obtained using a Student t test.