Table 2.

Frequency distribution of DNA ploidy diagnosis by degree of dysplasia in all lesions from the DNA ploidy subgroup, including index and nonindex lesions

Dysplasia gradeTotala
DNA ploidy diagnosisNone n (%)bMild n (%)bModerate n (%)bSevere n (%)bn (%)b
Diploid241 (52)93 (20)80 (17)47 (10)461 (100)
Tetraploid53 (54)17 (17)14 (14)14 (14)98 (100)
Aneuploid31 (18)18 (11)72 (42)49 (29)170 (100)
Total325 (45)128 (18)166 (23)110 (15)729 (100)

There is a statistically significant association between dysplasia grade and DNA ploidy, Pearson χ2 = 107.46, df = 6, P < 0.001.

  • aThis analysis includes 729 individual lesions of all types for which a valid result for DNA ploidy and dysplasia grade were available, and excludes those for which no follow-up data were available. This set of individual lesions includes both index and nonindex lesions and is not identifiable from Table 1, Table 4, or Fig. 2 (which show patient-based data). Nondysplastic lesions had all met the inclusion criteria and were considered suspicious on clinical grounds.

  • bPercentage of total lesions with a ploidy diagnosis.