Table 1.

Patient characteristics and analysis of RCC tumors grafted into nude mice

cRCC Patients characteristics
Patient numberAgeSexFuhrman gradeTumor greatest dimension (mm)MVD of RCC (number/field)Naftopidil/control CD31 positive MVD ratio
176M2253.4 ± 1.10.57
269M3314.8 ± 0.40.38
366F3306.8 ± 0.30.58
484F3305.0 ± 0.30.46
557M2205.0 ± 0.60.63
641M2604.6 ± 0.50.47
769M2284.6 ± 1.00.36
881M2374.0 ± 0.60.67
934M2505.0 ± 0.60.66
1060M3756.2 ± 0.90.71
1176M3357.7 ± 1.60.34
1280M3658.4 ± 3.10.53
1379F2445.5 ± 0.70.44
1466M2264.4 ± 0.40.21
1560M3358.0 ± 2.20.44
1666M3557.7 ± 1.70.62
1770F2117.7 ± 1.40.34
1878M2555.5 ± 1.10.61
1973F2224.4 ± 0.80.18
2077F2394.5 ± 0.60.36

NOTE: Demographics and MVD ratios of patients whose tumors were used in RCC xenografts. Twenty patients diagnosed with RCC underwent radical nephrectomy or partial nephrectomy. All patient with RCC tissues were obtained at the time of surgery and grafted into the bilateral renal capsule. All different RCC specimens remained engrafted successfully 35 days after transplantation. Values represent the mean ± SD.