Table 2.

The top over-represented transcripts in tumor between AC and AC+EX groups at 12 weeksa

TranscriptsSAM rankingUnigene or genome database name
Downregulated
FYB1FYN-binding protein
PAK42p21 protein (Cdc42/Rac)–activated kinase 4
TNFRSF10D3TNF receptor superfamily, member 10d, decoy with truncated death domain
Upregulated
KREMEN11Kringle-containing transmembrane protein 1
LOC4020572FROM EA: similar to 40S ribosomal protein S17 (LOC402057), mRNA.
SERPINA33Serpin peptidase inhibitor, clade A (α-1 antiproteinase, antitrypsin), member 3
NDUFS84NADH dehydrogenase (ubiquinone) Fe–S protein 8, 23kDa (NADH-coenzyme Q reductase)

aDownregulated pathways are those where gene-expression is lower in the AC+AET group compared with AC, whereas upregulated transcripts are those where gene-expression is higher in the AC+AET group compared with AC.