Table 1.

HPV16 and HPV18 antibody levels, at all visits, by vaccine-dose

3-dose2-dose0/12-dose0/61-dose3-dose2-dose0/12-dose0/61-dose
VisitHPV16 antibody levels (EU/mL)HPV18 antibody levels (EU/mL)
Geometric means
Enrollment<LODa<LOD<LOD<LOD<LOD<LOD<LOD<LOD
1484.59567.42NAb363.78207.85244.06NA207.01
6723.78655.45102.42145.27407.77510.9952.7275.79
122,035.95459.061,483.91114.82826.83258.24763.1970.60
241,115.26433.82837.19124.34470.77234.94446.0968.55
36899.16369.57641.86135.78369.30224.22357.6173.81
48748.25352.99519.99137.49334.55206.75304.9770.21
25th percentile
Enrollment<LOD<LOD<LOD<LOD<LOD<LOD<LOD<LOD
1212.37173.52NA151.7487.382.01NA87.65
6387.21340.1932.8957.6227.99224.1923.5431.09
121,075.52223.9849.6648.94387.03114.84445.7231.37
24641.08231.15492.7945.76261.56101.26195.6530.76
36493.39203.92362.1750.18214.17111.58181.3537.64
48438.17214.18283.9359.61200.42108.03155.0235.29
75th percentile
Enrollment<LOD<LOD<LOD<LOD<LOD8·87<LOD<LOD
1860.981,440.16NA491.02362.69452.26NA270.02
61,449.641,665.54278.15237.62739.992581.88111.18
123,784.49981.22,578.44242.321,659.59574.611,563.59126.28
241,948.35897.241,491.34277.31946.73502.92992.89135.85
361,674.05715.921,117.75265.8736.04463.97688.59112.34
481,359.28670.29944.39305624.36420.55551.12130.66
10th percentile
Enrollment<LOD<LOD<LOD<LOD<LOD<LOD<LOD<LOD
194.5186.97NA83.5549.9542.33NA42.57
6185.09172.1820.1327.38136.63137.78116.3113.09
12648.88119.265467.8422.81244.2667.00176.7018.23
24379.73117.17276.9332.76122.8162.57124.9315.469
36285.04103.185240.1432.27100.6058.61126.5718.924
48274.8397.14180.9436.8585.9950.8496.1318.05
90th percentile
Enrollment744.6230.65525.68<LOD12.3951.8310.2110.05
141,258.1512,704.86NA22,78.53714.813,254.77NA1,184.962
68,841.1912,822.651,115.711,969.531,520.912,090.46177.02310.551
1219,493.581,922.235,567.41730.162,519.341,152.092,348.99462.298
247,578.9421,588.881,928.73834.361,314.06967.921,304.85447.95
366,898.3081,400.061,723.84759.61,103.11875.681,117.35454.82
485,380.0971,160.31,345.07703.17970.32711.431,013.60358.99
  • aLOD, limit of detection.

  • bNA, not applicable—the two-dose group participants did not come for a 1-month visit, thus did not have blood drawn at 1 month for serological testing.