Table 1.

Summary of DMI, DEX, and ISO-induced tumor matrix alterations

Treatment (AR-selectivity)Tumor growthMetastasisSHG+ content (intensity)SHG+ fibers (% pixels)Total collagen (IF)
DMI (mixed AR)IncreasedNo changeIncreasedNo changeNo change
DEX (α2)IncreasedIncreasedNo changeIncreasedNo change
ISO (β-AR)No changeNo changeNo changeNo changeDecreased