Table 2.

Differentially expressed microRNAs obtained from HPV-negative versus HPV-positive tumors comparison by TLDA qRT-PCR

Card Probe IDMature miRFold changeAverageCt HPV negativeAverage Ct HPV positiveLocationa,b5′-3′ sequencea,cGene familyamRNA Targetsd
microRNAs with lower expression in HPV-positive tumors
hsa-miR-1291-002838hsa-miR-1291−2.327.5727.93Chr.12UGGCCCUGACUGAAGACCAGCAGUmiR-1291142
hsa-miR-342-3p-4395371hsa-miR-342-3p−2.5124.1723.08Chr.14UCUCACACAGAAAUCGCACCCGUmiR-342257
RNU44 − 001094RNU44−2.8921.5522.92Chr.1CCTGGATGATGATAGCAAATGCSmall Nuclear RNA
hsa-miR-193a-5p-4395392hsa-miR-193a-5p−2.1829.0528.79Chr.17UGGGUCUUUGCGGGCGAGAUGAmiR-193166
rno-miR-29c#-001818rno-miR-29c-5p−4.3829.2431.74Chr.13UGACCGAUUUCUCCUGGUGUUCmiR-29188
hsa-miR-106b#-002380hsa-miR-106b-3p−3.1429.1330.40Chr.7CCGCACUGUGGGUACUUGCUGCmiR-1714
hsa-miR-22#-002301hsa-miR-22-5p−2.9327.3829.60Chr.17AGUUCUUCAGUGGCAAGCUUUAmiR-22344
hsa-miR-365-4373194hsa-miR-365a-3p−2.4227.0727.17Chr.16UAAUGCCCCUAAAAAUCCUUAUmiR-365190
hsa-miR-151-5P-002642hsa-miR-151a-5p−2.4828.2229.18Chr.8UCGAGGAGCUCACAGUCUAGUmiR-2826
hsa-miR-144#-002148hsa-miR-144-5p−6.6129.1832.28Chr.17GGAUAUCAUCAUAUACUGUAAGmiR-144155
hsa-miR-125b-1#-002378hsa-miR-125b-1-3p−5.9427.4830.18Chr.11ACGGGUUAGGCUCUUGGGAGCUmiR-12511
hsa-miR-519b-3p-002384hsa-miR-519b-3p−146.3224.5331.53Chr.19AAAGUGCAUCCUUUUAGAGGUUmiR-515594
hsa-miR-26b#-002444hsa-miR-26b-3p−5.8532.6133.59Chr.2CCUGUUCUCCAUUACUUGGCUCmiR-26369
hsa-miR-19b-1#-002425hsa-miR-19b-1-5p−13.8430.4434.21Chr.13AGUUUUGCAGGUUUGCAUCCAGCmiR-19478
hsa-miR-1254-002818hsa-miR-1254-1−8.5326.8330.00Chr.10AGCCUGGAAGCUGGAGCCUGCAGUmiR-1254251
microRNAs with higher expression in HPV-positive tumors
hsa-miR-1274B-002884hsa-miR-1274be26.5821.5215.13Chr.19UCCCUGUUCGGGCGCCA**
hsa-miR-142-3p-4373136hsa-miR-142-3p7.3729.0326.17Chr.17UGUAGUGUUUCCUACUUUAUGGAmiR-142176
hsa-miR-21-4373090hsa-miR-21-5p5.723.7722.07Chr.17UAGCUUAUCAGACUGAUGUUGAmiR-21382
hsa-miR-708-4395452hsa-miR-708-5p3.2627.6625.59Chr.11AAGGAGCUUACAAUCUAGCUGGGmiR-708186
hsa-miR-16-4373121hsa-miR-16-5p3.6724.9321.21Chr.13UAGCAGCACGUAAAUAUUGGCGmiR-15611
hsa-miR-660-4380925hsa-miR-660-5p2.5727.9325.53Chr.XUACCCAUUGCAUAUCGGAGUUGmiR-188270
hsa-miR-29c-4395171hsa-miR-29c-5p3.0429.1825.83Chr.1UGACCGAUUUCUCCUGGUGUUCmiR-295
hsa-miR-1267-002885hsa-miR-12677.7723.9719.32Chr.13CCUGUUGAAGUGUAAUCCCCAmiR-1267209
hsa-miR-454-4395434hsa-miR-454-3p2.8827.5524.00Chr.17UAGUGCAAUAUUGCUUAUAGGGUmiR-454519
hsa-miR-186-4395396hsa-miR-186-5p2.1927.2123.96Chr.1CAAAGAAUUCUCCUUUUGGGCUmiR-1861313

*Data not found.