Table 1.

Baseline characteristics of study participants with baseline adenoma specimens in the exploratory and replication sets

Exploratory set (n = 20 subjects)aReplication set (n = 76 subjects)b
Age (y), mean ± SD66.0 ± 9.764.9 ± 9.3
Male sexc16 (80.0)48 (63.2)
Family history of colorectal cancerc4 (20.0)15 (20.6)
Current smokerc1 (5.00)6 (7.89)
Advanced adenomac12 (60.0)76 (100)
 Large adenoma (≥1 cm)11 (55.0)66 (86.8)
  High-grade dysplasia1 (5.00)10 (13.2)
   Villous histology7 (35.0)51 (67.1)
Any proximal adenomac6 (30.0)34 (47.2)
Multiple (≥3) adenomasc2 (10.0)24 (31.6)
Adenoma at follow-upc10 (50.0)40 (52.6)
  • aIncludes 20 subjects with colorectal adenomas.

  • bIncludes only participants at high risk of metachronous adenoma on the basis of presentation with ≥3 adenomas and/or an advanced adenoma (≥1.0 cm or with villous histology or high-grade dysplasia).

  • cNumber and percentage.