Table 1.

Hematology and serum biochemistry results for C57BL/6J male mice treated with Polyphenon E

VariablesUnitControl (n = 3)Low (n = 3)Medium (n = 3)High (n = 3)P value
WBC109/L5.83 ± 0.889.8 ± 1.856.97 ± 4.224.67 ± 1.690.27
Lymphocyte%81.4 ± 0.6882.9 ± 1.0677.5 ± 4.6377.1 ± 3.090.19
Monocyte%6.06 ± 0.125.03 ± 0.455.43 ± 0.345.97 ± 1.020.32
Granulocyte%12.5 ± 0.5712.1 ± 0.7417.1 ± 4.7416.9 ± 2.080.17
Hematocrit%36.96 ± 1.2238.43 ± 0.4637.93 ± 0.7038.6 ± 0.210.21
Hemoglobing/dL12.66 ± 0.3113.27 ± 0.2113.1 ± 0.1613.4 ± 0.080.04
Platelet109/L656.33 ± 33.2567.33 ± 33.87473.33 ± 117.03474.67 ± 156.20.28
BUNmg/dL26.1 ± 1.8027.1 ± 2.4024.23 ± 0.6924.13 ± 2.170.37
Creatininemg/dL<0.2<0.2<0.2<0.2
Phosphorusmg/dL7.2 ± 0.367.33 ± 0.588.03 ± 1.357.73 ± 0.610.73
Calciummg/dL10.3 ± 0.010.17 ± 0.0510.17 ± 0.1210.27 ± 0.170.33
Total proteing/dL5.6 ± 0.145.53 ± 0.195.43 ± 0.095.5 ± 0.080.67
Albuming/dL2.97 ± 0.052.97 ± 0.172.87 ± 0.122.86 ± 0.090.71
Globuling/dL2.63 ± 0.092.57 ± 0.052.57 ± 0.052.63 ± 0.050.55
Glucosemg/dL194.33 ± 9.03185.33 ± 7.13188.67 ± 4.50191.67 ± 15.860.83
ALTIU/L16.67 ± 0.4719.67 ± 1.7037.0 ± 21.9220.0 ± 0.820.22
ALPIU/L64.33 ± 2.8763.67 ± 5.3160.33 ± 1.8968.33 ± 2.620.31
GGTIU/L<10<10<10<10
Total bilirubinmg/dL0.1 ± 0.00.4 ± 0.140.17 ± 0.090.23 ± 0.090.07