Table 2.

Hematology and serum biochemistry results for TRAMP male mice treated with Polyphenon E

VariablesUnitControl (n = 3)Low (n = 5)Medium (n = 5)High (n = 6)P value
WBC109/L7.83 ± 1.217.48 ± 2.667.80 ± 2.228.36 ± 3.480.97
Lymphocyte%77.4 ± 3.8077.2 ± 3.8677.6 ± 4.9371.4 ± 5.530.20
Monocyte%6.60 ± 1.066.04 ± 1.015.86 ± 0.376.73 ± 0.670.37
Granulocyte%16.03 ± 2.7416.72 ± 3.0416.5 ± 4.7321.83 ± 5.050.20
Hematocrit%38.87 ± 1.5538.4 ± 0.9536.7 ± 1.0338.8 ± 0.880.05
Hemoglobing/dL13.1 ± 0.3313.08 ± 0.2412.5 ± 0.3413.1 ± 0.300.03
Platelet109/L713.3 ± 14.0663.0 ± 97.2523.8 ± 87.9477.7 ± 114.60.02
BUNmg/dL18.1 ± 0.1920.3 ± 4.217.28 ± 2.6319.9 ± 2.180.42
Creatininemg/dL<0.2<0.2<0.2<0.2
Phosphorusmg/dL6.9 ± 0.416.54 ± 0.807.20 ± 0.657.77 ± 0.680.09
Calciummg/dL10.6 ± 0.199.94 ± 0.3710.18 ± 0.1910.45 ± 0.050.01
Total proteing/dL5.8 ± 0.125.46 ± 0.225.40 ± 0.095.61 ± 0.180.06
Albuming/dL3.03 ± 0.092.84 ± 0.122.68 ± 0.042.90 ± 0.100.002
Globuling/dL2.73 ± 0.212.62 ± 0.122.72 ± 0.072.72 ± 0.180.71
Glucosemg/dL220.7 ± 5.79215.6 ± 21.3229.6 ± 21.18211.0 ± 19.630.55
ALTIU/L32.70 ± 4.1929.6 ± 19.433.6 ± 15.4922.5 ± 4.030.61
ALPIU/L66.7 ± 2.0571.8 ± 7.1457.4 ± 8.4867.33 ± 6.390.06
GGTIU/L<10<10<10<10
Total bilirubinmg/dL0.10 ± 0.00.14 ± 0.080.18 ± 0.100.12 ± 0.040.47