Table 3.

Fatty acid profile of RBCs stratified by prostate cancer progression status

Fatty acidaTotal (n = 48)Nonprogression (n = 34)Progression (n = 14)Pb
Total ω-30.70
 Mean ± SD7.96 ± 1.578.06 ± 1.697.71 ± 1.24
 Median (IQR)7.46 (7.17–8.59)7.47 (7.16–8.75)7.37 (7.23–8.24)
 ALA0.34
  Mean ± SD0.08 ± 0.090.09 ± 0.100.06 ± 0.09
  Median (IQR)0.00 (0.00–0.17)0.12 (0.00–0.17)0.00 (0.00–0.16)
 LC ω-30.98
  Mean ± SD7.86 ± 1.577.95 ± 1.717.65 ± 1.20
  Median (IQR)7.39 (7.08–8.41)7.40 (7.04–8.58)7.37 (7.23–8.10)
 EPA0.33
  Mean ± SD0.83 ± 0.430.87 ± 0.480.73 ± 0.28
  Median (IQR)0.82 (0.57–0.96)0.82 (0.59–0.98)0.69 (0.48–0.87)
 DPA0.40
  Mean ± SD2.64 ± 0.332.66 ± 0.362.57 ± 0.24
  Median (IQR)2.62 (2.45–2.77)2.63 (2.47–2.83)2.58 (2.43–2.72)
 DHA0.78
  Mean ± SD4.40 ± 1.094.42 ± 1.194.35 ± 0.81
  Median (IQR)4.15 (3.67–4.96)4.12 (3.61–5.03)4.34 (3.89–4.73)
Total ω-60.41
 Mean ± SD28.54 ± 1.8028.40 ± 1.9928.88 ± 1.23
 Median (IQR)28.82 (27.88–29.70)28.74 (27.64–29.58)29.13 (28.18–29.81)
ω-6/ω-3 ratio0.52
 Mean ± SD3.73 ± 0.793.69 ± 0.833.85 ± 0.69
 Median (IQR)3.88 (3.34–4.07)3.81 (3.29–4.07)3.89 (3.57–4.07)

NOTE: Prostate cancer progression is defined as biopsy-detected Gleason 7 at the first repeat biopsy session.

Abbreviation: LC ω-3, long-chain omega-3 fatty acids (EPA+DPA+DHA).

  • aFatty acids are expressed as a percentage of total fatty acids in the RBC membranes.

  • bP values were obtained by using the Fligner-Policello test.