Table 1.

Characteristics of the study subjects at the first repeat biopsy session

VariablesTotal (n = 48)Nonprogression (n = 34)Progression (n = 14)Pa
Age (y)0.52
 Mean ± SD60.0 ± 7.059.4 ± 6.561.3 ± 8.1
 Median (IQR)60.5 (55.0–66.0)60.0 (55.0–66.0)62.0 (55.0–66.0)
BMI (kg/m2)0.75
 Mean ± SD27.2 ± 3.327.1 ± 3.327.4 ± 3.5
 Median (IQR)27.6 (24.6–29.3)27.5 (24.4–29.2)27.8 (25.6–30.0)
Waist circumference (cm)0.94
 Mean ± SD95.9 ± 9.096.0 ± 8.995.7 ± 9.7
 Median (IQR)95.0 (89.0–103.5)96.0 (88.0–104.0)94.5 (89.0–103.0)
Education levelb (n, %)0.97
 Secondary school or less14 (30)10 (29)4 (33)
 Postsecondary diploma12 (26)9 (26)3 (25)
 University degree20 (44)15 (44)5 (42)
Smoking statusb (n, %)0.49
 Current smoker3 (7)3 (9)0 (0)
 Former smoker26 (57)18 (53)8 (67)
 Never17 (36)11 (38)4 (33)
PSA (ng/mL)0.81
 Mean ± SD4.6 ± 2.54.6 ± 2.74.4 ± 2.1
 Median (IQR)4.3 (3.0–5.0)4.3 (3.0–4.9)4.3 (2.8–5.0)
Positive biopsy cores (n)<0.0001
 Mean ± SD1.4 ± 1.41.0 ± 1.32.4 ± 1.1
 Median (IQR)1.0 (0.0–2.0)1.0 (0.0–1.0)2.0 (2.0–3.0)
Time intervalc (mo)0.12
 Mean ± SD3.6 ± 1.53.4 ± 1.53.9 ± 1.3
 Median (IQR)3.4 (2.4–4.3)3.2 (2.3–4.10)3.9 (2.7–4.9)

NOTE: In this study, 48 men diagnosed with low-risk prostate cancer and managed under active surveillance underwent a first repeat biopsy session. At the first repeat biopsy session, 14 men (29%) out of 48 had a progression of their cancer to Gleason 7 prostate cancer (progression group).

Bold font indicates significance at P < 0.05.

  • aP values were obtained by using the Fligner-Policello test for continuous variables and χ2 test for categorical variables.

  • bInformation was available for 46 patients out of 48.

  • cTime between the diagnostic biopsy and the first repeat biopsy session.