Table 1.

Patient characteristics

Flutamide (n = 12)Control (n = 47)
n (%)n (%)P
Age, yNS
 Mean ± SD (range)45.2 ± 8.4 (36–58)46.9 ± 9.1 (27–66)
MenopauseNS
 Yes3 (25)20 (43)
 No9 (75)26 (57)
BMINS
 Mean ± SD (range)26.2 ± 7.1 (19.3–45.0)28.9 ± 7.4 (20.1–56.2)
Number of pregnanciesNS
 02 (16)6 (13)
 1–39 (74)27 (59)
 ≥41 (8)13 (28)
Hormone replacement
 Estrogen onlyNS
  Ever1 (20)4 (11)
  Never4 (80)30 (88)
 Progesterone onlyNS
  Ever1 (20)0 (0)
  Never4 (80)34 (100)
 CombinedNS
  Ever2 (40)2 (6)
  Never3 (60)30 (93)
Oral contraceptive useNS
 Ever7 (58)33 (76)
 Never5 (42)10 (23)
EndometriosisNS
 Yes1 (8)2 (4)
 No11 (92)45 (96)
History of breast cancer<0.001
 Yes1 (8)33 (70)
 No11 (92)14 (30)
BRCA positiveNS
 Yes9 (75)19 (40)
 No2 (17)19 (40)
 Not tested1 (8)9 (19)
History of tubal ligation/hysterectomyNS
 Yes4 (33)14 (31)
 No8 (67)31 (69)

Abbreviations: BMI, body mass index; NS, not significant.