Table 2.

Summary of ROC analysis for a panel of four biomarkers (F5, EGFR, LRG1, and ITIH4)

Minimum number of positive markers to make positive diagnosisTime pointSensitivitySpecificityAUC
1 Positive6066.7%83.3%0.764
9085.7%90.0%0.900
135100%80.0%0.932
2 Positives6016.7%100%0.764
9042.9%100%0.843
13585.7%80.0%0.914
3 or more Positives600%100%0.764
9021.4%100%0.911
13578.6%90.0%0.904