Table 2.

Overall survival after oropharyngeal, base of tongue, and tonsil carcinoma by history of tonsillectomya

Any age<60 years≥60 years
History of tonsillectomyNcasesDeadHRb (95% CI)HRc (95% CI)NcasesDeadHRb (95% CI)HRc (95% CI)NcasesDeadHRb (95% CI)HRc (95% CI)
Oropharyngeal carcinoma overall
No tonsillectomy or tonsillitis4,8253,0641.001.002,5931,6011.001.002,2321,4631.001.00
Tonsillectomy <1 year before OPC174450.5 (0.4–0.6)0.6 (0.4–0.7)106240.4 (0.3–0.6)0.5 (0.3–0.8)68210.5 (0.4–0.7)0.6 (0.4–0.8)
Tonsillectomy ≥1 year before OPC52251.0 (0.7–1.5)1.3 (0.9–1.9)29131.4 (0.8–2.4)1.9 (1.1–3.2)23120.7 (0.4–1.3)1.0 (0.6–1.6)
Base of tongue carcinoma
No tonsillectomy or tonsillitis7274131.001.003862131.001.003412001.001.00
Tonsillectomy <1 year before base of tongue carcinoma1670.8 (0.4–1.5)1.0 (0.5–2.1)1040.8 (0.3–2.1)1.2 (0.4–3.3)630.9 (0.3–2.4)1.0 (0.4–2.8)
Tonsillectomy ≥1 year before base of tongue carcinoma1050.7 (0.3–1.8)1.0 (0.4–2.3)410.5 (0.07–3.7)0.7 (0.09–5.2)640.7 (0.3–1.9)1.1 (0.4–2.9)
Tonsil carcinoma
No tonsillectomy or tonsillitis2,6081,6231.001.001,4628681.001.001,1467551.001.00
Tonsillectomy <1 year before tonsil carcinoma123260.4 (0.3–0.6)0.5 (0.4–0.7)75150.4 (0.2–0.7)0.5 (0.3–0.8)48110.5 (0.3–0.7)0.5 (0.3–0.8)
Tonsillectomy ≥1 year before tonsil carcinoma1261.1 (0.5–2.3)1.3 (0.6–2.6)432.4 (0.8–7.3)2.1 (0.7–6.5)830.7 (0.3–1.8)0.9 (0.3–2.4)

NOTE: Bolded estimates are significant.

Abbreviation: OPC, oropharyngeal carcinoma.

  • aEstimates have been rounded to one significant digit for presentation in this table.

  • bCrude.

  • cAdjusted for attained age, calendar period, education and gender.