Table 3.

Prostate cancer risk by occupational physical activity (OPA)

Number of participants
TotalWithout PCaWith PCaIR per 1,000 person-yearAge-adjusted HR (95% CI)Multivariate HRa (95% CI)
Total PCa8,221
 Number of cases1,052
 Mostly sitting2,7994545.631.01.0
 Mostly standing1,0221485.010.89 (0.74–1.08)0.97 (0.80–1.17)
 Mostly on the move3,3484504.940.84 (0.74–0.96)0.91 (0.79–1.06)
Localized PCa7,872
 Number of cases703
 Mostly sitting2,7993063.951.01.0
 Mostly standing1,0221063.700.95 (0.76–1.19)1.01 (0.80–1.27)
 Mostly on the move3,3482913.220.81 (0.69–0.96)0.87 (0.72–1.04)
Advanced PCa7,518
 Number of cases349
 Mostly sitting2,7991482.001.01.0
 Mostly standing1,022421.560.77 (0.55–1.09)0.88 (0.62–1.26)
 Mostly on the move3,3481591.830.90 (0.72–1.12)1.01 (0.78–1.30)

Abbreviation: PCa, prostate cancer.

  • aAdjustment was made for the following covariates (values at baseline): birth-year, age, height, body mass index, type 2 diabetes, smoking, family history of prostate cancer, education, residency in early life, and regular health check-ups.

    Data on OPA were missing for 587 men.

    Number of individuals in multiadjusted analysis was 3% to 4% lower than in the age-adjusted analysis (due to missing values for covariates).