Table 1.

Body weight and serum 25-hydroxyvitamin D3, 1, 25-dihydroxyvitamin D3, and calcium

GroupsDietary vitamin D3 (IU/kg)Body weight (g)Serum 25D3 (ng/mL)Serum 1,25D3 (pg/mL)Serum calcium (mg/dL)
Acetone (S)2,00022.8 ± 0.920 ± 1.188 ± 18.39.90 ± 0.05
NTCU (SN)2,00018.1 ± 0.4b19 ± 0.588 ± 17.89.90 ± 0.27
NTCU + calcitriol (SN+C)2,00018.5 ± 0.410 ± 1.1c290 ± 12.7a,d9.97 ± 0.32
Acetone (D)022.7 ± 0.9<4 ± 0.2d43 ± 1.610.30 ± 0.20
NTCU (DN)019.4 ± 0.6<4 ± 0d40 ± 0.610.23 ± 0.27
NTCU + calcitriol (DN+C)019.0 ± 0.4b<4 ± 0d288 ± 26.5a,d9.40 ± 0.80

NOTE: Body weight is the mean ± SEM of the final weight of mice within a given group after 25 weeks of NTCU or control.

Serum 25D3 and calcium values are the mean ± SEM collected throughout the course of the experiment (4–30 weeks).

Serum 1,25D3 values are the mean ± SEM collected at 8, 24, and 30 weeks.

  • aReflects serum collected approximately 1 hour after calcitriol (1,25D3) treatments.

  • bP < 0.05 compared with Acetone (S).

  • cP < 0.005 compared with Acetone (S).

  • dP < 0.0001 compared with Acetone (S).