Table 4.

Significant (P < 0.05) changes in levels of 26 peptides and phosphopeptides in RPFNA specimens, assessed by RPPA

Number of paired specimens where levels
Protein (See Supplementary Table for gene name)Antibody name and specific phosphorylation siteDecreaseIncreaseP (Wilcoxona two-sided)
4E-BP14E-BP1_pS655110.049
4E-BP14E-BP1_pT37_T464120.0045
AktAkt_pS4733130.039
Bcl-2BCL21330.0072
C-RafC-Raf1330.039
Cyclin D1Cyclin D11150.044
Eukaryotic elongation factor 2 kinaseeEF2K4120.011
Eukaryotic initiation factor 4EeIF4E1420.0016
FibronectinFibronectin1330.0052
GATA binding protein 3GATA31330.023
Her-3HER31330.011
Myosin isoform IIaMyosin IIa_pS19431240.011
Phosphoinositide-dependent protein kinase 1PDK1_pS2414120.049
Phosphoprotein enriched in diabetes/phosphoprotein enriched in astrocytes—15 kDaPED/PEA15_pS1161240.023
Protein kinase c αPKC α2140.0038
Progesterone receptorProgesterone receptor1240.0027
Proline-rich Akt substratePRAS40_pT2461330.0027
Regulatory associated protein of mTORRaptor1330.0052
RbRb_pS807_S8115110.044
Stearoyl-CoA desaturaseSCD1330.0045
Smad3Smad31420.0023
SrcSrc_pY6273130.017
Stat5aStat5a1150.044
Spleen tyrosine kinaseSyk1420.013
Transglutaminase IITGM21150.044
TuberinTSC2 Tuberin_pT14624120.0061
  • aP-values <0.01 are indicated in bold.