Table 4.

Change in quantitative measures assessed by pelvic sonography and DEXA from baseline to postintervention

Variable or biomarkerBaselinePostinterventionChangeP
Pelvic ultrasonography
 Endometrial thickness, mm660.00.40
2–261–17−11–5
[4–9][3.5–8][−3–2]
7.6 ± 5.56.3 ± 4.0−0.7 ± 3.9
 Endometrial evaluation as abnormal0%0%0%1.00
 Ovarian cyst largest diameter, mm122314<0.001
0–260–54−19–49
[0–19][16–35.5][3.5–24.5]
10.5 ± 9.525.6 ± 14.415.1 ± 15.4
 Ovarian cysts present
  Any15 (60%)23 (92%)8 (32%)0.011
  >30 mm0 (0%)9 (36%)9 (36%)0.003
 Fibroid largest diameter, mm0000.47
0–160–25−15–9
[0–0][0–0][0–0]
2.3 ± 5.51.8 ± 6.3−0.52 ± 4.4
 Fibroids present4 (16%)2 (8%)2 (8%)0.16
DEXA
 Lumbar spine bone mineral density, g/cm21.281.24−0.05<0.001
1.09–1.481.07–1.42−0.11–0.03
[1.19–1.37][1.17–1.30][−0.07–−0.02]
1.28 ± 0.111.24 ± 0.09−0.05 ± 0.04
 Lumbar spine T-score0.700.30−0.40<0.001
−0.8–2.3−1.2–1.9−1.1–0.3
[0–1.4][−0.25–0.9][−0.6–−0.2]
0.69 ± 0.840.30 ± 0.78−0.39 ± 0.30
 Femur bone mineral density, g/cm20.991.03−0.010.48
0.80–1.280.88–1.35−0.06–0.36
[0.94–1.15][0.95–1.18][−0.02–0.01]
1.04 ± 0.131.05 ± 0.140.016 ± 0.08
 Femur T-score−0.2−0.1−0.10.68
−1.7–2.2−1.1–2.7−0.60–2.90
[−0.6–1.1][−0.5–1.4][−0.2–0.1]
0.25 ± 1.030.36 ± 1.100.11 ± 0.69
 Percent body fat35.837.50.30.76
16.7–54.219.3–54.7−4.0–5.8
[31.3–46.1][31.2–46.7][−1.7–2.4]
37.0 ± 9.437.8 ± 9.90.3 ± 2.6

NOTE: For quantitative measures, median, range, [IQR], and mean ± SD are shown for the 25 subjects. For categorical indices, the number and percentage are shown.