Table 3.

Hematologic values and clinical chemistry values of the preventive study on the induced mammary tumorigenesis in rats

PFPE
NormalControlVehicle100 mg/kg200 mg/kg
Hematologic values
 White blood cells (×103/μL)2.90 ± 0.813.15 ± 1.713.45 ± 0.302.58 ± 0.383.60 ± 0.70
 Neutrophil (%)85.25 ± 4.8373.13 ± 12.1779.17 ± 2.0683.00 ± 1.6974.63 ± 3.29
 Lymphocyte (%)14.75 ± 4.8325.75 ± 11.9417.67 ± 2.2015.60 ± 1.3222.75 ± 2.68
 Monocyte (%)0.00 ± 0.000.50 ± 1.072.33 ± 0.421.20 ± 0.801.88 ± 1.01
 Eosinophil (%)0.00 ± 0.000.62 ± 0.920.50 ± 0.220.20 ± 0.130.75 ± 0.41
 Basophil (%)0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
 Red blood cells (×106/μL)6.82 ± 0.366.29 ± 0.506.36 ± 0.276.43 ± 0.146.28 ± 0.20
 Hemoglobin g/dl)13.79 ± 0.5113.60 ± 0.9013.52 ± 0.5213.46 ± 0.3313.10 ± 0.42
 Hematocrit (%)38.53 ± 1.7436.21 ± 3.0537.22 ± 1.6136.60 ± 0.9036.53 ± 0.74
 Mean corpuscular volume (fl)56.55 ± 1.0459.35 ± 2.6258.55 ± 0.3756.86 ± 0.3458.35 ± 0.90
 Mean corpuscular hemoglobin (pg)20.25 ± 0.6121.45 ± 0.6921.32 ± 0.2520.91 ± 0.2020.86 ± 0.18
 Mean corpuscular hemoglobin concentration (g/dl)35.82 ± 0.7836.78 ± 1.0935.71 ± 0.3436.78 ± 0.2035.81 ± 0.55
 Platelet (×105/μL)546.75 ± 59.88512.63 ± 96.94522.33 ± 30.76527.00 ± 18.01510.02 ± 18.79
Clinical blood chemistry values
 BUN (mg/dl)22.93 ± 3.7632.04 ± 10.0426.43 ± 1.2122.92 ± 0.5027.43 ± 1.66
 Creatinine (mg/dl)0.57 ± 0.130.52 ± 0.130.62 ± 0.070.54 ± 0.030.61 ± 0.04
 Total protein (g/dl)6.77 ± 0.475.57 ± 0.366.34 ± 0.216.61 ± 0.146.51 ± 0.11
 Albumin (g/dl)3.42 ± 0.203.11 ± 0.243.35 ± 0.053.35 ± 0.043.34 ± 0.05
 Total bilirubin (mg/dl)0.20 ± 0.110.33 ± 0.140.32 ± 0.090.21 ± 0.040.30 ± 0.06
 SGOT (U/L)109.83 ± 21.14179.38 ± 31.56105.17 ± 8.16112.50 ± 6.58116.88 ± 9.91
 SGPT (U/L)55.00 ± 17.7256.38 ± 11.3560.33 ± 9.0448.70 ± 2.6048.38 ± 6.51
 Alkaline phosphatase (U/L)82.33 ± 20.42123.88 ± 30.12102.17 ± 9.37108.90 ± 15.75116.38 ± 19.59

Abbreviations: SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic pyruvic transaminase.